• About
  • Submit Article/PR
  • Contact
Saturday, March 25, 2023
No Result
View All Result
  • Login
The Healthcare Daily
WHO COVID DASHBOARD
  • Home
  • News
    • All
    • Biotech
    • By Speciality
    • Generic Drugs
    • Insurance
    • Investment
    • Medical Tourism
    • Pharma
    What-Chronic-Disease-Management-Is-All-About-How-to-Deal-with-It-Healthcare-Daily

    What Chronic Disease Management Is All About & How to Deal with It

    cancer-cure-TheHealthcareDaily

    Cancer Cure: Is there a cure for it?

    Womens-Reproductive-Rights-Around-the-world-Healthcare-Daily

    Women’s Reproductive Rights Around the World : Rights 101

    Everything-about-Telehealth-reimbursement-and-insurance-coverage-Healthcare-Daily

    Absolutely Everything about Telehealth Reimbursement and Coverage : Healthcare 101

    Everything-about-Personalized-Medicine-in-2023-Healthcare-Daily

    Everything about Personalized Medicine in 2023

    Healthcare cost containment and insurance reform

    Healthcare cost containment and insurance reform

    Understanding Chronic Diseases: Symptoms, Causes, and Treatment Options

    The Most Common Dental Mistakes in Healthcare Industry

    The 6 Most Common Dental Mistakes in Healthcare Industry

    How To Get a Dental Checkup for Free (or Cheap)

    How To Get a Dental Checkup for Free (or Cheap)

  • Insights
    • All
    • Analysis
    • Interview
    • Opinion
    • Reports
    Workforce-Diversity-and-its-5-Benefits-in-healthcare-Daily

    Workforce Diversity and it’s 5 Benefits in healthcare

    Healthcare-Affordability-in-United-States-Healthcare-101-Daily

    Healthcare Affordability in United States : Healthcare 101

    The-Benefits-and-Challenges-of-Data-and-Analytics-in-Healthcare-Daily

    The Benefits and Challenges of Data and Analytics in Healthcare

    Healthcare-Industry-At-A-Glance-Healthcare-DAily

    Healthcare Industry At A Glance

    7-Reasons-Millennials-Are-The-Most-Disruptive-Generation-Yet-Healthcare-Daily

    7 Reasons Millennials Are The Most Disruptive Generation Yet

    Technological-challenges-faced-by-pharma-companies-today-Healthcare-Daily

    Technological challenges faced by Pharma Companies Today

    Senior living options in Canada

    Senior living options in Canada in 2022

    A Guide to Medical Tourism in India: Everything You Need to Know

    A Guide to Medical Tourism in India: Everything You Need to Know

    5 Things to know before adopting a child

    Adoption: 5 Things to know before going for a successful child adoption

  • HealthTech
    • All
    • Hardware
    • Innovation
    • Software
    Overview-of-healthcare-hackathons-and-competitions-focused-on-healthcare-innovation-thehealthcaredaily

    Overview of healthcare hackathons and competitions focused on healthcare innovation

    Everything-about-Telehealth-reimbursement-and-insurance-coverage-Healthcare-Daily

    Absolutely Everything about Telehealth Reimbursement and Coverage : Healthcare 101

    Everything-about-Personalized-Medicine-in-2023-Healthcare-Daily

    Everything about Personalized Medicine in 2023

    5-Amazing-Advancements-in-Medical-Technology-2023-Healthcare-Daily

    5 Amazing Advancements in Medical Technology 2023

    Pros-and-Cons-of-Telemedicine-Healthcare-Daily

    Pros and Cons of Telemedicine in Healthcare 2023

    The-Benefits-and-Challenges-of-Data-and-Analytics-in-Healthcare-Daily

    The Benefits and Challenges of Data and Analytics in Healthcare

    Healthcare workforce and talent management

    Healthcare workforce and talent management

    Healthcare cost containment and insurance reform

    Healthcare cost containment and insurance reform

    Telehealth and digital health solutions

    Telehealth and digital health solutions

  • Pharma
  • Events
  • NewsMakers
  • World
  • Home
  • News
    • All
    • Biotech
    • By Speciality
    • Generic Drugs
    • Insurance
    • Investment
    • Medical Tourism
    • Pharma
    What-Chronic-Disease-Management-Is-All-About-How-to-Deal-with-It-Healthcare-Daily

    What Chronic Disease Management Is All About & How to Deal with It

    cancer-cure-TheHealthcareDaily

    Cancer Cure: Is there a cure for it?

    Womens-Reproductive-Rights-Around-the-world-Healthcare-Daily

    Women’s Reproductive Rights Around the World : Rights 101

    Everything-about-Telehealth-reimbursement-and-insurance-coverage-Healthcare-Daily

    Absolutely Everything about Telehealth Reimbursement and Coverage : Healthcare 101

    Everything-about-Personalized-Medicine-in-2023-Healthcare-Daily

    Everything about Personalized Medicine in 2023

    Healthcare cost containment and insurance reform

    Healthcare cost containment and insurance reform

    Understanding Chronic Diseases: Symptoms, Causes, and Treatment Options

    The Most Common Dental Mistakes in Healthcare Industry

    The 6 Most Common Dental Mistakes in Healthcare Industry

    How To Get a Dental Checkup for Free (or Cheap)

    How To Get a Dental Checkup for Free (or Cheap)

  • Insights
    • All
    • Analysis
    • Interview
    • Opinion
    • Reports
    Workforce-Diversity-and-its-5-Benefits-in-healthcare-Daily

    Workforce Diversity and it’s 5 Benefits in healthcare

    Healthcare-Affordability-in-United-States-Healthcare-101-Daily

    Healthcare Affordability in United States : Healthcare 101

    The-Benefits-and-Challenges-of-Data-and-Analytics-in-Healthcare-Daily

    The Benefits and Challenges of Data and Analytics in Healthcare

    Healthcare-Industry-At-A-Glance-Healthcare-DAily

    Healthcare Industry At A Glance

    7-Reasons-Millennials-Are-The-Most-Disruptive-Generation-Yet-Healthcare-Daily

    7 Reasons Millennials Are The Most Disruptive Generation Yet

    Technological-challenges-faced-by-pharma-companies-today-Healthcare-Daily

    Technological challenges faced by Pharma Companies Today

    Senior living options in Canada

    Senior living options in Canada in 2022

    A Guide to Medical Tourism in India: Everything You Need to Know

    A Guide to Medical Tourism in India: Everything You Need to Know

    5 Things to know before adopting a child

    Adoption: 5 Things to know before going for a successful child adoption

  • HealthTech
    • All
    • Hardware
    • Innovation
    • Software
    Overview-of-healthcare-hackathons-and-competitions-focused-on-healthcare-innovation-thehealthcaredaily

    Overview of healthcare hackathons and competitions focused on healthcare innovation

    Everything-about-Telehealth-reimbursement-and-insurance-coverage-Healthcare-Daily

    Absolutely Everything about Telehealth Reimbursement and Coverage : Healthcare 101

    Everything-about-Personalized-Medicine-in-2023-Healthcare-Daily

    Everything about Personalized Medicine in 2023

    5-Amazing-Advancements-in-Medical-Technology-2023-Healthcare-Daily

    5 Amazing Advancements in Medical Technology 2023

    Pros-and-Cons-of-Telemedicine-Healthcare-Daily

    Pros and Cons of Telemedicine in Healthcare 2023

    The-Benefits-and-Challenges-of-Data-and-Analytics-in-Healthcare-Daily

    The Benefits and Challenges of Data and Analytics in Healthcare

    Healthcare workforce and talent management

    Healthcare workforce and talent management

    Healthcare cost containment and insurance reform

    Healthcare cost containment and insurance reform

    Telehealth and digital health solutions

    Telehealth and digital health solutions

  • Pharma
  • Events
  • NewsMakers
  • World
No Result
View All Result
The Healthcare Daily
No Result
View All Result

Brain On Fire: A Rare Autoimmune Disease

A rare autoimmune encephalitis that drove neurologists stunned with its extravagant symptoms.

by THD Desk
June 17, 2022
in Featured, Health, Neurology
Reading Time: 4 mins read
0
Brain On Fire: A Rare Autoimmune Disease

The Second Angle

0
SHARES
Share on FacebookShare on Twitter

Ever wondered that the Netflix film “Brain on Fire” was based on the true story of Susannah Cahalan. The condition she went through was not exclusively extremely unusual, but also very complicated to diagnose at that time.

She suffered from an autoimmune disease of the brain, which is medically termed as Anti — N-methyl-D-Aspartate (Anti — NMDA) Receptor Encephalitis. After being successfully treated she released a book named “Brain on Fire: My Month of Madness” in 2012 to uncover her journey as a patient, the hardships she went through before getting the right medications, inaccurate diagnosis, and educating the public about the severity of the Anti — NMDA Receptor Encephalitis. 

Film review: Brain on Fire – Chloe Grace Moretz confronts rare brain disease in monotonous drama | South China Morning Post
scmp

What is Anti — NMDA Receptor Encephalitis

The NMDA is the glutamate receptor present on the neurons and acts as an ion transporter for the conduction of impulses to and from the brain. It moreover keeps the Dopamine levels in check, which is essential for the proper functioning of the brain.

The hypo functioning of NMDA glutamate synapse causes an increase in dopamine levels in the brain which results in Psychotic Symptoms like loss of behavior control, motor controls of the brain, concentration issues, memory loss, etc.

Dopamine dysregulation has been further linked to schizophrenia, attention-deficit hyperactivity disorder (ADHD), bipolar disorder.

Brain on fire disease is autoantibody-mediated encephalitis, which was first identified in 2007. 

An autoimmune neurological disorder in which antibodies developed in the body which are supposed to attack the pathogens causing the disease starts to attack its own body and in this case antibodies binds with NMDA receptor present in the neurons of the brain and causes dysfunction and blockage in the glutamate synapse which outcomes in the disorder named as (anti — NMDA) Receptor Encephalitis.

The disease has been associated with the presence of underlying conditions like cancer, tumors (Ovarian Teratoma generally), infections (Herpes Simplex Encephalitis most commonly reported), etc.

Women and children are susceptible to this rare disease, with approximately 80 percent of cases recorded being of females and children in comparison to men.   

Anti–NMDA Receptor Encephalitis - Neuroimaging Clinics
Neuroimaging Clinics

Symptoms of Anti — NMDA Receptor Encephalitis

The symptoms of Anti — NMDA Receptor Encephalitis occur in phases that may begin as a normal headache and rapidly modify into neuropsychiatric issues within the weeks. The signs are entirely based on the acuteness of the disease.

Various acute symptoms encountered by the patients of this ailment are described below:

  • Cognitive Impairments like confusion, lack of concentration, difficulty in perceiving and comprehending thoughts, decreased level of consciousness, etc.
  • Behavioral Changes like mood swings, disorganized thoughts, hallucination, paranoia, hearing voices, etc.
  • Seizures
  • Movement Disorders like Tardive dyskinesia (involuntary movements of the muscles of trunk, limbs, face, etc as seen in the patients with a withdrawal syndrome)
  • Autonomic Instability (a life-threatening condition in which neurons regulating the involuntary muscles of the body are damaged as of heart, blood vessels, digestive system, etc)  
  • Comatose
Brain on Fire: Puzzling brain disease could now be better diagnosed and treated - Neuroscience News
Neuroscience News

Atypical symptoms commonly found in children are as follows:

  • Cerebellar ataxia (loss of muscle control and coordination due to damage in the cerebellum) 
  • Hemiparesis (mild but partial paralysis of one side of the body)

Treatments to cure “Brain on Fire”

Similar to the symptoms, the treatment of the Anti-NMDA Receptor Encephalitis also exists in phases. The first-line treatments include procedures to eradicate the causative agents of the disease, and second-line treatments consist of drugs to suppress the symptoms elicited due to the illness.

Some First-line treatments include:

  • Steroids (Oral or Intravenous)
  • Intravenous Immunoglobulins (IVIG)
  • Plasma Exchange (Dialysis)
Brain On Fire: A Rare Autoimmune Disease
IMDb

A few notable Second-line treatments are:

  • Immunosuppressants (crucial therapy to cure autoimmune disorders)
  • Cyclophosphamide (reduces inflammation) 
  • Rituximab (a monoclonal antibody)
  • Epileptic drugs to relieve the Seizures.
  • Antipsychotic/Neuroleptic drugs

Besides the treatment described above, it is vital to rule out the underlying factors like strokes, tumors, intoxications that contribute to stimulating the severity of Anti — NMDA Receptor Encephalitis.

 

Source: https://thesecondangle.com/brain-on-fire-a-rare-autoimmune-disease/

 

Also Read: The Refreshing Lemon Has Much More To Offer

THD Desk

THD Desk

Next Post
The Refreshing Lemon Has Much More To Offer

The Refreshing Lemon Has Much More To Offer

Recommended

Thrusting districts oppose malnutrition with a boost of Rs1.4L Crore

Policy Intervention set to counter malnutrition with a boost of Rs 1.4 L Crore

2 years ago
Cholesterol: 5 lifestyle changes you’ll implement in your life if you too have high cholesterol

Cholesterol: 5 lifestyle changes you’ll implement in your life if you too have high cholesterol

2 years ago

About Us

A daily dose of news, views, opinions, and actionable information from the global healthcare industry. Our newsletter is available for a limited audience. If you are interested to write or contribute to this portal then please get in touch.

Contact Us

Medianiti Ltd, Brooklands Business Park, Wellington Way, Weybridge KT13 0TT,
United Kingdom
General: hello@thehealthcaredaily.com

Important Links

  • Home
  • World
  • Business
  • Health

Recent News

In-depth coverage of global healthcare policy initiatives and their potential impact on the industry

Overview of healthcare hackathons and competitions focused on healthcare innovation

  • About
  • Submit Article/PR
  • Contact

© 2020 THP - A Medianiti Venture.

No Result
View All Result
  • Home
  • World
  • Business
  • Health

© 2020 THP - A Medianiti Venture.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In